COMPANY MANAGEMENT

Lowell Sears LOWELL E. SEARS is Chairman, Chief Executive Officer and Chief Investment Officer of Sears Capital Management, Inc. Mr. Sears has been a venture investor and portfolio manager through Sears Capital Management since 1994. From 1988 until 1994 Mr. Sears was Chief Financial Officer of Amgen, Inc. In addition to his role as CFO with Amgen, Mr. Sears also held the position of Senior Vice President responsible for the Asia Pacific Region, establishing marketing, sales and development operations in Japan, China, and other countries from 1992 through 1994. From 1986 until 1988 Mr. Sears served as Treasurer and Director of Planning for Amgen. Before joining Amgen Mr. Sears held senior planning and financial positions with Atlantic Richfield Company (ARCO) from 1976 until 1986, including a period as Chief Financial Officer for its Ventures Division. Mr. Sears has been an active participant in the pharmaceutical and medical device industries since 1979.

Mr. Sears holds a BA in Economics from Claremont McKenna College and an MBA from the Stanford University Graduate School of Business.

BOARDS OF DIRECTORS

PUBLIC COMPANIES

CoCensys, Inc. (COCN): Neurological Disorders
Chairman of the Board 1996-1998
Board Member 1994-1998
Audit Committee, Chairman 1994-1998

Dendreon, Inc. (DNDN): Cancer/Immunology
Board Member 1995-2000
Audit Committee, Chairman 1995-2000
Compensation Committee Member 1995-1999

Techne Corporation (TECH): Research Reagents
Board Member 1994-2003
Audit Committee Member 1994-2003

Neose Technologies (NTEC): Carbohydrate Rx
Board Member 1994-2007
Audit Committee, Chairman 1994-2007
Corporate Governance Committee Member 2002-2007

Vital Therapies, Inc. (VTL): Liver Disease
Board Member: 2013-2019
Audit Committee, Chairman 2013-2019
Compensation Committee, 2013-2019
SymBio Pharmaceuticals, KK (JASDAQ 4582): Cancer Therapeutics
Board Member 2005-2017

Novacea Pharmaceuticals, Inc (NOVC): Oncology Rx
Board Member 2004-2008
Audit Committee, Chairman 2004-2008

PRIVATE COMPANIES

SiteOne Therapeutics, Inc.: Pain Management
Chairman of the Board: 2014-2024

Halcyon Medical, Inc.: Interventional Cardiovascular
Board Member: 2014-2021

InteKrin Therapeutics.: Metabolic Disorder
Chairman of the Board 2005-2010
Audit Committee, Chairman 2005-2011

Cellerant Therapeutics, Inc.: Cancer
Chairman of the Board: 2012-2017
Audit Committee, Chairman 2012-2017

Novalar Pharmaceuticals, Inc.: Dental Therapeutics
Board Member 2000-2011
Audit Committee, Chairman 2001-2011

Corthera Inc.: Cardiovascular/Renal
Board Member 2004-2010
Compensation Committee Member 2004-2010

Coapt Systems, Inc.: Surgical Closure/Fixation Devices
Chairman of the Board 2000-2002
Board Member 2000-2008
Audit Committee, Chairman 2001-2008

Anthera Pharmaceuticals, Inc.: Pulmonary/Cardiovascular
Chairman of the Board 2004-2008
Audit Committee, Chairman 2007-2008

Asthmatx

Asthmatx, Inc.: Interventional Device - Asthma Therapy
Board Member 2006-2007
Audit Committee, Chairman 2006-2007

Saroynx, Inc.: Preclinical/Toxicology Services
Board Member 2000-2005
Compensation Committee Member 2000-2005

Cerexa, Inc.: Anti-infectives
Board Member 2005

Peninsula Pharmaceuticals, Inc.: Anti-infectives
Board Member 2002-2005
Audit Committee, Chairman 2002-2005
Corporate Governance, Chairman 2003-2005

Encore Pharmaceuticals, Inc.: Cancer Therapeutics
Board Member 1998-2000

Elitra Pharmaceuticals, Inc.: Bacterial Genomics
Board Member 1999-2002
Audit Committee, Chairman 1999-2002

OverRead, Inc

Overread, Inc.: Medical Imaging Services
Board Member 1999-2002

Asilomar Pharmaceuticals: Anti-virals/Analgesics: PNS
Board Member 2002-2004

Integrated Biosystems, Inc.: Biological Manufacturing Eq.
Co-Chairman of the Board 1997-1999
Board Member 1997-2004
Audit Committee, Chairman 1997-2004